Pieber T R, Holler A, Siebenhofer A, Brunner G A, Semlitsch B, Schattenberg S, Zapotoczky H, Rainer W, Krejs G J
Department of Internal Medicine, Karl-Franzens-University, Graz, Austria.
Diabet Med. 1995 Apr;12(4):349-54. doi: 10.1111/j.1464-5491.1995.tb00491.x.
The efficacy of a treatment and teaching programme for non-insulin-treated Type 2 diabetic patients in general practice was evaluated in a prospective, controlled study. In a rural area in southern Austria, 53 patients from seven general practices participated in a structured programme (intervention group) and 55 patients from seven general practices without the programme served as the control group. After 6 months the weight reduction in the intervention group was 2.6 kg (1.6-3.7 kg, p < 0.001) and the difference in HbA1c between the groups was 0.92% (0.23-1.61%, p < 0.01) at follow-up. Systolic (-16.6 mmHg) and diastolic (-11.1 mmHg) blood pressure, serum triglycerides (-0.63 mmol I-1), and serum cholesterol (-0.40 mmol I-1) were reduced significantly in the intervention group (p < 0.006). The number of patients with callus formation and poor nail care decreased significantly after participating in the teaching programme (p < 0.001). In the control group no reduction in body weight, metabolic control or in risk factors for diabetic foot complications were observed. Calculated health care costs per patient and year decreased in the intervention group (-33 pounds) and increased in the control group (+ 30 pounds) mainly due to changes in prescription of oral hypoglycaemic agents in both groups. This programme may be an efficient and helpful model to increase overall quality of diabetes care according to the St Vincent Declaration.
在一项前瞻性对照研究中,对非胰岛素治疗的2型糖尿病患者在全科医疗中的治疗与教学计划的疗效进行了评估。在奥地利南部的一个农村地区,来自7家全科诊所的53名患者参与了一个结构化计划(干预组),来自7家未实施该计划的全科诊所的55名患者作为对照组。6个月后,干预组体重减轻2.6千克(1.6 - 3.7千克,p < 0.001),随访时两组间糖化血红蛋白差异为0.92%(0.23 - 1.61%,p < 0.01)。干预组收缩压(-16.6毫米汞柱)和舒张压(-11.1毫米汞柱)、血清甘油三酯(-0.63毫摩尔/升)和血清胆固醇(-0.40毫摩尔/升)显著降低(p < 0.006)。参与教学计划后,胼胝形成和指甲护理不佳的患者数量显著减少(p < 0.001)。在对照组中,未观察到体重、代谢控制或糖尿病足并发症危险因素的降低。主要由于两组口服降糖药处方的变化,干预组每位患者每年的医疗保健费用下降(-33英镑),而对照组上升(+ 30英镑)。根据《圣文森特宣言》,该计划可能是提高糖尿病护理整体质量的有效且有益的模式。