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具有动脉瘤的血管中非线性脉动悬浮流动力学的有限元分析

Finite element analysis of nonlinear pulsatile suspension flow dynamics in blood vessels with aneurysm.

作者信息

Kumar B V, Naidu K B

机构信息

Department of Mathematics and Computer Science, Sri Sathya Sai Institute of Higher Learning, India.

出版信息

Comput Biol Med. 1995 Jan;25(1):1-20. doi: 10.1016/0010-4825(95)98881-d.

Abstract

A nonlinear pulsatile suspension flow in a dilated vessel is numerically analysed. Two sets of highly coupled nonlinear partial differential equations governing the suspension flow are numerically solved, to simulate the suspension flow dynamics. A transient velocity-pressure (UVP) finite element method (FEM) and a stable time integration scheme, based on a predictor-corrector strategy, with constant error monitoring are employed in the flow analysis. The pulsatile suspension flow is characterized by analysing the flow, pressure and stress fields. Effects of the nonlinear particulate phase on the nonlinear suspending fluid phase are brought out by comparing the suspension flow results with those of homogeneous flow. Particles are seen to dampen the flow velocity, wall and central axis pressure, pressure gradient and wall shear stress. time-dependent recirculation regions which are sensitive to the presence of particles are seen in the dilated portion of the vessel. These recirculation regions favour thrombogenesis. The nonlinear effects due to the vessel geometry and those due to the convective terms dominate the dampening effect of the particles. These nonlinear effects are depicted through the transverse velocity and pressure plots. Wall shear stresses of suspension flow are not only high but also alternate in direction.

摘要

对扩张血管中的非线性脉动悬浮流进行了数值分析。通过数值求解两组控制悬浮流的高度耦合非线性偏微分方程,来模拟悬浮流动力学。在流动分析中采用了基于预测 - 校正策略且具有恒定误差监测的瞬态速度 - 压力(UVP)有限元方法(FEM)和稳定的时间积分方案。通过分析流动、压力和应力场来表征脉动悬浮流。通过将悬浮流结果与均匀流结果进行比较,揭示了非线性颗粒相对非线性悬浮流体相的影响。可以看到颗粒会抑制流速、壁面和中心轴压力、压力梯度以及壁面剪应力。在血管的扩张部分可以看到对颗粒存在敏感的随时间变化的回流区域。这些回流区域有利于血栓形成。由于血管几何形状和对流项引起的非线性效应主导了颗粒的阻尼效应。这些非线性效应通过横向速度和压力图来描绘。悬浮流的壁面剪应力不仅很高,而且方向交替变化。

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