al-Hazzaa S A, Specht C S, McLean I W, Harris D J
Department of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, D.C., USA.
Cornea. 1995 May;14(3):316-20.
We report the clinical and scanning electron microscopic findings in an older adult patient with unilateral posterior keratoconus. Clinically, the cornea showed typical posterior concavity with focal underlying anterior ectasia and an epithelial iron ring. Scanning electron microscopy of the cornea removed at penetrating keratoplasty revealed a pericentral posterior concavity. The endothelial layer was intact, with moderate endothelial cell pleomorphism. There were no excrescences of Descemet's membrane or endothelial tags. The lack of discrete irregularities on the posterior corneal surface in this case is different from previous descriptions of the pathological appearance of posterior keratoconus, which have been used to support a relationship of this condition to central corneal mesenchymal dysgenesis. This is the first report of scanning electron microscopic findings in posterior keratoconus.
我们报告了一例老年单侧后圆锥角膜患者的临床及扫描电子显微镜检查结果。临床上，角膜呈现典型的后凸，伴有局灶性下方前弹力层膨隆及上皮铁环。穿透性角膜移植术中取下的角膜进行扫描电子显微镜检查显示中央周边后凸。内皮细胞层完整，内皮细胞有中度多形性。后弹力层无赘生物或内皮细胞附着。该病例角膜后表面缺乏离散的不规则性，这与先前关于后圆锥角膜病理表现的描述不同，先前描述曾用于支持这种情况与中央角膜间充质发育异常的关系。这是后圆锥角膜扫描电子显微镜检查结果的首例报告。
