Brewitt H
Klin Monbl Augenheilkd. 1979 Apr;174(4):605-13.
An acute keratoconus was examined for the first time using a scanning electron microscope. The alterations in the epithelium of the cornea consisted of a reduction in microvilli and microplicae structures, disruption of the intercellular spaces with raised protrusions of epithelial cells in the region of the peak of the keratoconus or even of the complete disappearance of all regular surface structures. In the stroma distinct irregularities in the lamellae, sometimes even the formation of cavities in the region of the cornea peak, could be seen. These findings correlate well with the light microscope pictures and with the published transmission electron microscopic results.
首次使用扫描电子显微镜对急性圆锥角膜进行检查。角膜上皮的改变包括微绒毛和微皱襞结构减少,细胞间隙破坏,在圆锥角膜顶点区域上皮细胞出现凸起,甚至所有正常表面结构完全消失。在基质中,可以看到板层明显不规则,有时在角膜顶点区域甚至形成空洞。这些发现与光学显微镜图像以及已发表的透射电子显微镜结果高度相关。