Horiguchi M, Miyake Y, Kondo M, Suzuki S, Tanikawa A, Koo H M
Department of Ophthalmology, Nagoya University School of Medicine, Japan.
Invest Ophthalmol Vis Sci. 1995 Jul;36(8):1730-2.
To develop a contact lens electrode with a built-in blue light-emitting diode (LED) to record the electroretinogram from short-wave sensitive-cone (S-cone) electroretinogram (ERG) in humans.
The ERG was recorded using the blue LED (450 nm) built-in electrode under a yellow background illumination from a slide projector in five normal subjects, a patient with blue cone monochromatism, and a patient with fundus albipunctatus. For comparison, the ERG was also recorded using a yellow LED (566 nm) built-in electrode under the same background illumination in the normal subjects.
The amplitude and the peak time of the b-wave recorded with 3-Hz blue stimuli were 5.1 to 12.4 microV and 63 to 68 msec, respectively in normal subjects, 7.3 microV and 65 msec in the patient with blue cone monochromatism, and 11.4 microV and 65 msec in the patient with fundus albipunctatus. Normal subjects responded to neither 30-Hz blue stimuli nor 3-Hz yellow stimuli.
Results indicate that the b-wave recorded with 3-Hz blue stimuli is elicited from the S-cone system. This simple technique is useful for testing the human blue cone system.
研发一种内置蓝光发光二极管（LED）的隐形眼镜电极，用于记录人类短波敏感视锥细胞（S-视锥细胞）视网膜电图（ERG）。
在五名正常受试者、一名蓝锥单色视患者和一名白点状眼底患者中，使用内置蓝色LED（450纳米）电极在幻灯机发出的黄色背景照明下记录ERG。为作比较，也在正常受试者中使用内置黄色LED（566纳米）电极在相同背景照明下记录ERG。
在正常受试者中，用3赫兹蓝色刺激记录的b波振幅和峰值时间分别为5.1至12.4微伏和63至68毫秒，蓝锥单色视患者为7.3微伏和65毫秒，白点状眼底患者为11.4微伏和65毫秒。正常受试者对30赫兹蓝色刺激和3赫兹黄色刺激均无反应。
结果表明，用3赫兹蓝色刺激记录的b波由S-视锥细胞系统引出。这种简单技术对检测人类蓝锥细胞系统有用。
