Stevens R D, Seguin B E, Momont H W
Department of Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA.
J Am Vet Med Assoc. 1995 Jul 15;207(2):214-6.
Cloprostenol was administered IV or IM to diestrous dairy cows to study luteolysis and synchrony of estrus and ovulation. In Study 1, 28 Holstein cows were assigned to receive injections of cloprostenol, IV or IM, on day 8 or 10 of the estrous cycle. Differences in cloprostenol-induced luteolysis or interval to estrus, were not detected. Ultrasonography revealed that 2 cows treated IV on day 8, 1 cow treated IM on day 8, and 2 cows treated IV on day 10 did not ovulate despite evidence of an apparently normal estrus. In Study 2, 20 Holstein cows were assigned to receive cloprostenol injections, IV or IM, on day 10 of the estrous cycle. Interval to estrus was not affected by route of administration. Analysis of these data indicated that cloprostenol given IV did not alter luteolysis or improve synchrony of estrus and ovulation when compared with cloprostenol given IM.
对处于发情后期的奶牛静脉注射或肌肉注射氯前列醇，以研究黄体溶解以及发情和排卵的同步性。在研究1中，28头荷斯坦奶牛被分配在发情周期的第8天或第10天接受静脉注射或肌肉注射氯前列醇。未检测到氯前列醇诱导的黄体溶解或发情间隔的差异。超声检查显示，尽管有明显正常发情的迹象，但在第8天接受静脉注射的2头奶牛、在第8天接受肌肉注射的1头奶牛以及在第10天接受静脉注射的2头奶牛均未排卵。在研究2中，20头荷斯坦奶牛被分配在发情周期的第10天接受静脉注射或肌肉注射氯前列醇。发情间隔不受给药途径的影响。对这些数据的分析表明，与肌肉注射氯前列醇相比，静脉注射氯前列醇不会改变黄体溶解或改善发情和排卵的同步性。
