美国一般参考数据库中VNTR基因座D5S110的固定箱式频率分布。
Fixed bin frequency distributions for the VNTR locus D5S110 in general United States reference databases.
作者信息
Budowle B, Giusti A M
机构信息
Forensic Science Research and Training Center, FBI Academy, Quantico, VA, USA.
出版信息
J Forensic Sci. 1995 Mar;40(2):236-8.
Fixed bin frequencies for the D5S110 locus were determined in African Americans, Caucasians, Southeastern Hispanics, and Southwestern Hispanics. The data were generated by RFLP analysis of HAE III-digested genomic DNA. The D5S110 locus met Hardy-Weinberg expectations in the four sample populations, and there is no evidence for association of alleles between the D5S110 and other routinely used VNTR loci. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in various general United States populations.
在非裔美国人、高加索人、东南部西班牙裔和西南部西班牙裔群体中确定了D5S110基因座的固定等位基因频率。数据通过对经HAE III消化的基因组DNA进行限制性片段长度多态性（RFLP）分析产生。D5S110基因座在这四个样本群体中符合哈迪-温伯格平衡预期，并且没有证据表明D5S110与其他常规使用的可变数目串联重复序列（VNTR）基因座之间的等位基因存在关联。这些频率数据可用于法医分析和亲子鉴定，以估计美国不同普通人群中DNA图谱的频率。
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