将微囊化丝裂霉素C经动脉体外注入犬肾。
Ex vivo intra-arterial infusion of microencapsulated mitomycin C into dog kidney.
作者信息
Kato T, Nemoto R, Nishimoto T
出版信息
Tohoku J Exp Med. 1979 Jan;127(1):99-100. doi: 10.1620/tjem.127.99.
PMID:760256
Abstract
Microencapsulated Mitomycin C with ethylcellulose was infused into isolated dog kidneys through the renal artery. The capsules were lodged mainly at cortico-medullary junction, where the drug was released from the capsules. Vascularity of kidney was reduced moderately.
摘要
将含有丝裂霉素C的乙基纤维素微囊通过肾动脉注入离体狗肾。微囊主要滞留在皮质-髓质交界处，药物从微囊中释放出来。肾脏的血管分布有适度减少。
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