Ishizawa E, Horiuchi T, Ito T, Yamaki S, Sato K, Sato N, Tanaka S, Suzuki Y, Tadokoro M
Tohoku J Exp Med. 1979 Feb;127(2):189-95. doi: 10.1620/tjem.127.189.
This paper presents our recent results of the Mustard procedure (intra-artrial baffle operation) for the complete transposition of the great arteries performed in 24 infants and children during the past 6 years at the Tohoku University Hospital. All intracardiac repairs were performed using "bypass hypothermia" (surface-induced deep hypothermia, circulatory arrest, and limited cardiopulmonary bypass). The hospital mortality rate was 8% in patients with simple transposition without pulmonary hypertension (Group I, one death in 12 patients), 50% in patients with ventricular septal defect (VSD) and pulmonary hypertension (Group II, 3 deaths in 6 patients), and 20% in patients with VSD and pulmonary stenosis (Group III, one death in 5 patients). Various types of longstanding dysrhythmia were found in 6 out of 18 long-term survivors, and subsequent pace-maker implantation was necessary in one infant. Postoperative pulmonary venous obstruction occurred in 3 infants, and surgical relief of the obstruction was successfully undertaken in 2 of them. Prevention of postoperative dysrhythmia, pulmonary venous obstruction, and possible brain damage are also discussed.
本文介绍了我们在过去6年里于东北大学医院为24例婴幼儿和儿童实施的用于完全性大动脉转位的Mustard手术(心房内挡板手术)的近期结果。所有心内修复手术均采用“体外循环低温法”(体表诱导深度低温、循环停止和有限的心肺转流)。无肺动脉高压的单纯性转位患者(第一组,12例中有1例死亡)的医院死亡率为8%,室间隔缺损(VSD)合并肺动脉高压的患者(第二组,6例中有3例死亡)的死亡率为50%,VSD合并肺动脉狭窄的患者(第三组,5例中有1例死亡)的死亡率为20%。18例长期存活者中有6例出现了各种类型的长期心律失常,1例婴儿随后需要植入起搏器。3例婴儿发生了术后肺静脉梗阻,其中2例成功地进行了梗阻的手术解除。还讨论了术后心律失常、肺静脉梗阻和可能的脑损伤的预防。