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近期采用“体外循环低温技术”行Mustard手术治疗完全性大动脉转位的经验。

Recent experiences with the Mustard procedure for the complete transposition of the great arteries by means of "bypass hypothermia".

作者信息

Ishizawa E, Horiuchi T, Ito T, Yamaki S, Sato K, Sato N, Tanaka S, Suzuki Y, Tadokoro M

出版信息

Tohoku J Exp Med. 1979 Feb;127(2):189-95. doi: 10.1620/tjem.127.189.

Abstract

This paper presents our recent results of the Mustard procedure (intra-artrial baffle operation) for the complete transposition of the great arteries performed in 24 infants and children during the past 6 years at the Tohoku University Hospital. All intracardiac repairs were performed using "bypass hypothermia" (surface-induced deep hypothermia, circulatory arrest, and limited cardiopulmonary bypass). The hospital mortality rate was 8% in patients with simple transposition without pulmonary hypertension (Group I, one death in 12 patients), 50% in patients with ventricular septal defect (VSD) and pulmonary hypertension (Group II, 3 deaths in 6 patients), and 20% in patients with VSD and pulmonary stenosis (Group III, one death in 5 patients). Various types of longstanding dysrhythmia were found in 6 out of 18 long-term survivors, and subsequent pace-maker implantation was necessary in one infant. Postoperative pulmonary venous obstruction occurred in 3 infants, and surgical relief of the obstruction was successfully undertaken in 2 of them. Prevention of postoperative dysrhythmia, pulmonary venous obstruction, and possible brain damage are also discussed.

摘要

本文介绍了我们在过去6年里于东北大学医院为24例婴幼儿和儿童实施的用于完全性大动脉转位的Mustard手术(心房内挡板手术)的近期结果。所有心内修复手术均采用“体外循环低温法”(体表诱导深度低温、循环停止和有限的心肺转流)。无肺动脉高压的单纯性转位患者(第一组,12例中有1例死亡)的医院死亡率为8%,室间隔缺损(VSD)合并肺动脉高压的患者(第二组,6例中有3例死亡)的死亡率为50%,VSD合并肺动脉狭窄的患者(第三组,5例中有1例死亡)的死亡率为20%。18例长期存活者中有6例出现了各种类型的长期心律失常,1例婴儿随后需要植入起搏器。3例婴儿发生了术后肺静脉梗阻,其中2例成功地进行了梗阻的手术解除。还讨论了术后心律失常、肺静脉梗阻和可能的脑损伤的预防。

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