[Influence of local hyperthermia induced by micro-waves and X-rays on the Walker carcinoma of the rat (author's transl)].

The authors studied the influence on the solid Walker carcinoma in the rat exerted by a slight local hyperthermia induced by micro-waves, which was applied alone and combined with X-ray irradiations. It could be demonstrated that the tumor has the same temperature as the sub-peritoneal region. Thus the final temperature reached by the treatment with micro-waves can be exactly controlled. Heating up to 41 degrees C for 30 minutes produces an increase of the survival rate of animals with tumors of 2 to 6 grams from 17% to 27%, whereas the healing rate is 57% after an X-ray irradiation with 1130 rad and 75% after the combined treatment. Each of the three therapy methods produces a significant prolongation of the survival time of the dying animals. The disadvantages of an anisologic tumor-host system are discussed on the basis of the results achieved.