Rubin A M, Liedgren S R, Odkvist L M, Larsby B, Aschan G
Acta Otolaryngol. 1979 Jan-Feb;87(1-2):113-22. doi: 10.3109/00016487909126395.
The input from fore- and hindlimbs to the vestibular nuclear complex (VNC) was investigated in awake cats. Electrical stimulus was given to the sciatic, radial and vestibular nerves bilaterally and single unit responses were recorded in the VNC with extracellular technique. The position of the microelectrode was histologically confirmed. All four major vestibular nuclei received fore- as well as hindlimb input. Forty per cent of the neurons with limb input also received vestibular afferents. No major distinguishing features appeared between the different nuclei with regard to response characteristics. Certain differences in laterality of response, quantitative fore-hindlimb ratio and somatosensory-labyrinthine convergence were observed however. Response latencies to sciatic and radial nerve stimuli always exceeded a 3 msec and were grouped around 8 and 16 msec. A third population of vestibular neurons had latencies over 20 msec. Both excitatory and inhibitory responses were recorded, with the latter not always following an activation. The findings illustrate the complex nature of the ascending pathway to the VNC and the integrative properties of this complex.
在清醒猫中研究了前肢和后肢向前庭神经核复合体（VNC）的输入。双侧对坐骨神经、桡神经和前庭神经施加电刺激，并采用细胞外技术在VNC中记录单单位反应。微电极的位置通过组织学方法得以确认。所有四个主要前庭核均接受前肢和后肢的输入。40%接受肢体输入的神经元也接受前庭传入。不同核团在反应特征方面未出现主要的区别特征。然而，在反应的偏侧性、前肢与后肢定量比例以及躯体感觉与迷路传入的汇聚方面观察到了某些差异。对坐骨神经和桡神经刺激的反应潜伏期总是超过3毫秒，集中在8毫秒和16毫秒左右。第三群前庭神经元的潜伏期超过20毫秒。记录到了兴奋性和抑制性反应，后者并非总是跟随激活而出现。这些发现说明了通往VNC的上行通路的复杂性以及该复合体的整合特性。
