Peyman G A, Schulman J A, Sullivan B
LSU Eye Center, New Orleans, USA.
Surv Ophthalmol. 1995 Mar-Apr;39(5):375-95. doi: 10.1016/s0039-6257(05)80093-1.
Perfluorocarbon liquids have been used to facilitate surgery in a wide variety of conditions, including proliferative vitreoretinopathy, giant retinal tears, drainage of suprachoroidal hemorrhages, diabetic traction, retinal detachments with a rhegmatogenous component, dislocated crystalline or intraocular lenses, and retinal detachment associated with choroidal coloboma. The clarity of perfluorocarbon liquids, with a refractive index close to that of water, allows the use of a conventional contact lens for vitreous surgery while the low viscosity facilitates tissue manipulation, injection, and removal. All perfluorocarbon liquids when used as tamponading agents can compress and disorganize the retina. This "toxicity" is a physical effect rather than chemical toxicity and depends upon the amount of perfluorocarbon liquid injected. Perfluorocarbon liquids are not tolerated in the anterior chamber, causing corneal edema within 2-3 days at the site of contact.
全氟碳液体已被用于多种情况下的手术辅助，包括增生性玻璃体视网膜病变、巨大视网膜裂孔、脉络膜上腔出血引流、糖尿病性牵拉、伴有孔源性成分的视网膜脱离、晶状体或人工晶状体脱位以及与脉络膜缺损相关的视网膜脱离。全氟碳液体的透明度高，其折射率接近水的折射率，这使得在玻璃体手术中可以使用传统的接触镜，同时其低粘度便于组织操作、注射和移除。所有用作填塞剂的全氟碳液体都会压迫视网膜并使其结构紊乱。这种“毒性”是一种物理效应而非化学毒性，它取决于注入的全氟碳液体的量。前房不能耐受全氟碳液体，接触部位会在2至3天内出现角膜水肿。
