Daif A, Awada A, al-Rajeh S, Abduljabbar M, al Tahan A R, Obeid T, Malibary T
Division of Neurology, King Saud University, Riyadh, Saudi Arabia.
Stroke. 1995 Jul;26(7):1193-5. doi: 10.1161/01.str.26.7.1193.
We undertook this study to determine the frequency, clinical patterns, and etiologies of cerebral venous thrombosis in a Middle Eastern country.
Records of all adults patients admitted with an angiographically documented diagnosis of cerebral venous thrombosis from 1985 through 1994 in two major hospitals of Riyadh, Saudi Arabia, were reviewed.
Forty patients (20 men, 20 women) aged 16 to 40 years were identified. Hospital frequency was 7 per 100,000 patients, and the relative frequency against arterial strokes was 1:62.5. Nineteen cases (47%) had a clinical picture of pseudotumor cerebri. Behçet's disease was the cause in 10 cases (25%). Other causes included antiphospholipid antibodies in 4, protein S deficiency in 3, intracranial tumors in 3, systemic lupus erythematosus in 3, infections in 3, antithrombin III deficiency in 2, postpartum in 1, and oral contraceptives in 1.
Cerebral venous thrombosis in adults is not uncommon in Saudi Arabia. Behçet's disease is the single most common etiology. Infection is no longer an important cause, whereas "new" coagulation disorders are common. Patients with a pseudotumor cerebri syndrome should undergo angiography or brain MRI before being labeled idiopathic.
我们开展这项研究以确定中东某国脑静脉血栓形成的发生率、临床模式及病因。
回顾了沙特阿拉伯利雅得市两家主要医院1985年至1994年期间所有经血管造影确诊为脑静脉血栓形成的成年患者的记录。
共确定了40例患者（20例男性，20例女性），年龄在16至40岁之间。医院发生率为每100,000例患者中有7例，与动脉性卒中的相对发生率为1:62.5。19例（47%）有假脑瘤的临床表现。10例（25%）病因是白塞病。其他病因包括抗磷脂抗体4例、蛋白S缺乏3例、颅内肿瘤3例、系统性红斑狼疮3例、感染3例、抗凝血酶III缺乏2例、产后1例、口服避孕药1例。
在沙特阿拉伯，成人脑静脉血栓形成并不少见。白塞病是最常见的单一病因。感染不再是重要病因，而“新的”凝血障碍很常见。有假脑瘤综合征的患者在被诊断为特发性之前应进行血管造影或脑部磁共振成像检查。
