Song J T, Rozanski T A, Belville W D
Department of Surgery, University of Michigan Medical Center, Ann Arbor 48109-0330, USA.
Urology. 1995 Jul;46(1):81-4. doi: 10.1016/S0090-4295(99)80164-2.
This work demonstrates a simple technique utilizing a fiberoptic microtransducer that provides statistically reproducible stress leak point pressure (SLPP) results without the use of fluorourodynamics.
Nineteen stress incontinent patients with varied clinical histories underwent two SLPP measurements on 2 separate days, totaling four data points. A 14 F catheter sheath was inserted to empty the bladder. Through this sheath, a 5 F fiberoptic microtransducer was inserted into the bladder and zeroed. Then, 250 cc of indigo-carmine solution was instilled, during which a filling cystometrogram was performed. The sheath was removed, leaving only the 5 F transducer in the bladder. A 2 by 2 inch gauze was placed at the meatus. As each participant performed a slow Valsalva maneuver, an event marker was used to note the pressure at which indigo solution was first seen to stain the gauze.
SLPPs ranged from 15 to 140 cm water (H2O). A two-tailed paired t test demonstrated no statistical difference (P < 0.6) between the two SLPPs performed on day 1, with a mean difference of 1.05 +/- 2.61 (95% confidence interval [CI]). Comparison of the two SLPPs performed on day 2 also revealed no statistical difference (P < 0.8), with a mean difference of -0.17 +/- 5.65 (95% CI). Lastly, comparison of the mean SLPPs from day 1 with the mean SLPPs from day 2 revealed no statistically significant difference (P < 0.8), with the mean difference of -0.59 +/- 1.62 (95% CI).
This study demonstrates a simple technique that produces reproducible SLPP measurements in a wide variety of clinical settings and avoids ionizing radiation.
本研究展示了一种利用光纤微传感器的简单技术，该技术无需使用尿动力学检查即可提供具有统计学可重复性的应力性漏点压力（SLPP）结果。
19例有不同临床病史的压力性尿失禁患者在2个不同日期接受了两次SLPP测量，共获得四个数据点。插入一个14F的导管鞘排空膀胱。通过该鞘管，将一个5F的光纤微传感器插入膀胱并归零。然后注入250cc靛胭脂溶液，在此期间进行充盈性膀胱测压。移除鞘管，仅将5F传感器留在膀胱内。在尿道口放置一块2×2英寸的纱布。当每位参与者进行缓慢的瓦尔萨尔瓦动作时，使用事件标记记录首次看到靛蓝溶液使纱布染色时的压力。
SLPP范围为15至140厘米水柱（H2O）。双尾配对t检验显示，第1天进行的两次SLPP之间无统计学差异（P<0.6），平均差异为1.05±2.61（95%置信区间[CI]）。对第2天进行的两次SLPP的比较也显示无统计学差异（P<0.8），平均差异为-0.17±5.65（95%CI）。最后，比较第1天的平均SLPP与第2天的平均SLPP，未发现统计学显著差异（P<0.8），平均差异为-0.59±1.62（95%CI）。
本研究展示了一种简单技术，该技术可在多种临床环境中产生可重复的SLPP测量结果，并避免了电离辐射。
