[使用血管紧张素转换酶抑制剂进行肾血管性高血压的放射性核素诊断]

[The radionuclide diagnosis of vasorenal hypertension using an angiotensin-converting enzyme inhibitor].

作者信息

Vozianov A F, Shcherbak A Iu, Prishchepa P P, Zubko V I, Guts R V, Sabadash A S

出版信息

Lik Sprava. 1994 Sep-Dec(9-12):64-8.

Abstract

Conventional routine renography and dynamic renoscintigraphy fail to yield sufficient diagnostic criteria in vasorenal hypertension, being associated with 21.5% false negative and 33.3% false positive results. Capoten induces statistically significant functional changes manifested by worsening of time-associated indicators of secretory-excretory function of the kidney, glomerular filtration rate and effective renal plasma flow on the side of the unilateral renal artery stenosis; relative hypotension in this situation leads to a statistically insignificant improvement of functional activity of the contralateral kidney parenchyma.

摘要

传统的常规肾图检查和动态肾闪烁造影在肾血管性高血压中未能产生足够的诊断标准，其假阴性率为21.5%，假阳性率为33.3%。卡托普利可引起具有统计学意义的功能变化，表现为单侧肾动脉狭窄侧肾脏分泌-排泄功能、肾小球滤过率和有效肾血浆流量的时间相关指标恶化；在这种情况下，相对低血压导致对侧肾实质功能活动的改善在统计学上无显著意义。