Bauer H C, Brosjö O, Kreicbergs A, Lindholm J
Department of Orthopedics, Karolinska Hospital, Stockholm, Sweden.
Acta Orthop Scand. 1995 Jun;66(3):283-8. doi: 10.3109/17453679508995543.
We analyzed the clinical course in 40 patients with enchondroma and 40 with low-grade chondrosarcoma of the extremities after a median follow-up of 7 years. 13 patients with enchondroma and 2 with chondrosarcoma had only open biopsy and they had no signs of further progression of the lesions. Among 23 patients with enchondroma and 23 with chondrosarcoma who were treated by intralesional curettage, 3 had local recurrences. The 10-year local recurrence rate was 0.04 in the enchondroma group and 0.09 in the chondrosarcoma group. There were no metastases. The results imply that enchondroma and low-grade chondrosarcoma of the extremities should be treated with limited surgery. The morbidity associated with en bloc resection and reconstruction can apparently be obviated without jeopardizing the limb or survival.
我们对40例内生软骨瘤患者和40例四肢低度软骨肉瘤患者进行了分析,中位随访时间为7年。13例内生软骨瘤患者和2例软骨肉瘤患者仅接受了开放活检,且病变无进一步进展迹象。在23例接受病灶内刮除术治疗的内生软骨瘤患者和23例软骨肉瘤患者中,3例出现局部复发。内生软骨瘤组10年局部复发率为0.04,软骨肉瘤组为0.09。均无转移。结果表明,四肢内生软骨瘤和低度软骨肉瘤应采用有限手术治疗。在不危及肢体或生存的情况下,显然可以避免大块切除和重建相关的发病率。