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刮除术和冷冻手术治疗良性及低度恶性髓内软骨样肿瘤

Treatment of benign and low-grade malignant intramedullary chondroid tumours with curettage and cryosurgery.

作者信息

Schreuder H W, Pruszczynski M, Veth R P, Lemmens J A

机构信息

Department of Orthopaedics, University Hospital Nijmegen, The Netherlands.

出版信息

Eur J Surg Oncol. 1998 Apr;24(2):120-6. doi: 10.1016/s0748-7983(98)91459-7.

Abstract

AIMS

To shed light on the controversy surrounding the methods of evaluating, staging and final treatment of intramedullary chondroid lesions. Controversy particularly exists for enchondroma and low-grade chondrosarcoma located in the extremities, because their accurate distinction is hampered by their radiographical and histological similarity.

METHODS

Since 1991 we have treated 22 patients (mean age: 39.6 years) with 26 lesions (three chondroblastomas, 14 enchondromas and nine grade 1 chondrosarcomas) with curettage, cryosurgery and bone grafting.

RESULTS

After a mean follow-up of 26 months no recurrences were observed. Complications consisted of two post-operative fractures, one wound infection and one intraoperative venous gas embolism. All bone grafts incorporated, resulting in full weight-bearing capacity and excellent functional results.

CONCLUSION

The usefulness of a combination of curettage and cryosurgery as adjuvant therapy is considered to be equal to marginal resection according to orthopaedic oncological principles. The pre-operative assessment of these lesions and cryosurgical technique is described in detail.

摘要

目的

阐明围绕髓内软骨样病变评估、分期及最终治疗方法的争议。特别是位于四肢的内生软骨瘤和低级别软骨肉瘤存在争议,因为它们在影像学和组织学上的相似性阻碍了准确区分。

方法

自1991年以来,我们对22例患者(平均年龄:39.6岁)的26处病变(3例软骨母细胞瘤、14例内生软骨瘤和9例1级软骨肉瘤)采用刮除、冷冻手术及骨移植进行治疗。

结果

平均随访26个月后未观察到复发情况。并发症包括2例术后骨折、1例伤口感染和1例术中静脉气体栓塞。所有骨移植均愈合,恢复了完全负重能力且功能结果良好。

结论

根据骨科肿瘤学原则,刮除术与冷冻手术联合作为辅助治疗的有效性被认为等同于边缘切除。详细描述了这些病变的术前评估及冷冻手术技术。

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