Binutu O A, Lajubutu B A
Department of Pharmacognosy, College of Medicine, University of Ibadan, Nigeria.
Afr J Med Med Sci. 1994 Sep;23(3):269-73.
The methanol extracts of the leaves and stem bark of four Bignoniaceae plants Jacaranda mimosifolia D. Dol., Tecoma stans Linn., Tabebuia rosea (Bertol) D.C., and Crescentia cujete Linn. were studied for their antimicrobial activity using a wide range of Gram-positive and Gram-negative bacteria and fungi. Extracts of both the leaves and stem bark of majority of plant species studied showed variable but remarkable broad spectrum antimicrobial activity. However, methanol extracts of Tecoma stans leaves was found to be effective against only Candida albicans at the concentrations employed. It was observed that the extracts of stem bark generally showed better antimicrobial activity than those of the leaves and some organisms were selectively more sensitive to the extracts than others. Preliminary phytochemical screening of these plants revealed the presence of tannins, flavonoids, alkaloids, quinones and traces of saponins. The antimicrobial activity observed are discussed in relation to the chemical constituents reportedly isolated from these plants and their traditional uses.
对紫葳科的四种植物——蓝花楹（Jacaranda mimosifolia D. Dol.）、黄钟花（Tecoma stans Linn.）、粉花风铃木（Tabebuia rosea (Bertol) D.C.）和葫芦树（Crescentia cujete Linn.）的叶和茎皮的甲醇提取物，使用多种革兰氏阳性菌、革兰氏阴性菌和真菌研究了它们的抗菌活性。所研究的大多数植物物种的叶和茎皮提取物均表现出不同但显著的广谱抗菌活性。然而，在所采用的浓度下，黄钟花叶的甲醇提取物仅对白色念珠菌有效。据观察，茎皮提取物的抗菌活性通常比叶提取物更好，并且一些生物体对提取物的敏感性比其他生物体更高。对这些植物进行的初步植物化学筛选显示存在单宁、黄酮类化合物、生物碱、醌类和微量皂苷。结合据报道从这些植物中分离出的化学成分及其传统用途，对观察到的抗菌活性进行了讨论。
