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加纳药用植物的化学成分与抗菌活性:腊肠决明、巴氏血檀、无刺帽柱木和科氏假香椿。

Chemical constituents and antimicrobial activity of medicinal plants from Ghana: Cassia sieberiana, Haematostaphis barteri, Mitragyna inermis and Pseudocedrela kotschyi.

作者信息

Asase Alex, Kokubun Tetsuo, Grayer Renée J, Kite Geoffrey, Simmonds Monique S J, Oteng-Yeboah Alfred A, Odamtten George T

机构信息

Department of Botany, University of Ghana, P.O. Box LG55 Legon-Accra, Ghana.

出版信息

Phytother Res. 2008 Aug;22(8):1013-6. doi: 10.1002/ptr.2392.

DOI:10.1002/ptr.2392
PMID:18618525
Abstract

The antimicrobial activity of the sequential n-hexane, acetone and 50% aqueous methanol extracts of leaves, stem bark and roots of four species of medicinal plants, Cassia sieberiana DC. (Leguminosae), Haematostaphis barteri Hook. f. (Anacardiaceae), Mitragyna inermis (Willd.) O. Kuntze (Rubiaceae) and Pseudocedrela kotschyi (Schweinf.) Harms (Meliaceae), from Ghana were tested against Bacillus subtilis, Pseudomonas syringae and Cladosporium herbarum using TLC direct-autobiographic methods. Extracts from leaves, stem bark and roots of the four species gave a positive result against at least one test organism. Twelve of the 36 extracts were active against B. subtilis, four extracts were active against P. syringae and six were active against C. herbarum. Preliminary chemical analysis revealed the presence of flavonoids, stilbenes and alkaloids. This is the first report of a stilbene from the Anacardiaceae.

摘要

采用薄层色谱直接自显影法,对来自加纳的4种药用植物,即决明(豆科)、巴氏血胶木(漆树科)、无刺帽蕊木(茜草科)和科氏假香椿(楝科)的叶、茎皮和根依次用正己烷、丙酮和50%甲醇水溶液提取得到的提取物,进行了抗枯草芽孢杆菌、丁香假单胞菌和草本枝孢菌的抗菌活性测试。这4种植物的叶、茎皮和根提取物对至少一种测试微生物呈阳性结果。36种提取物中有12种对枯草芽孢杆菌有活性,4种提取物对丁香假单胞菌有活性,6种对草本枝孢菌有活性。初步化学分析表明存在黄酮类、芪类和生物碱。这是漆树科中首次报道有芪类。

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