Nikiforov Iu V, Griaznov S V
Anesteziol Reanimatol. 1995 Jan-Feb(1):25-8.
The parameters of central hemodynamics and oxygen balance were studied over the course of prolonged venovenous hemofiltration (VVHF) in 16 patients with the syndrome of multiorgan failure (acute renal, pulmonary, cardiovascular insufficiency and shock), which developed after open heart surgery. The measurements were carried out 3, 8, 16, and 25 h after VVHF was started. The rate of ultrafiltration was 30 to 60 ml/min. Stabilization of arterial pressure (diastolic and mean) and normalization of the total peripheral vascular resistance were observed in all the patients irrespective of the status of the central hemodynamics before hemofiltration session. The doses of catecholamines with the predominant vasopressor effect were reduced. Integrative parameters of cardiorespiratory delivery and consumption of oxygen were unchanged. Addition of VVHF to a complex of intensive care measures used in patients with the multiorgan failure syndrome helped attain satisfactory results in 9 (56%) patients. Seven (44%) patients died in various periods after VVHF, shock occurring in 6 of them.
对16例心脏直视手术后发生多器官功能衰竭综合征（急性肾、肺、心血管功能不全及休克）的患者，在延长的静脉-静脉血液滤过（VVHF）过程中研究了中心血流动力学和氧平衡参数。在VVHF开始后3、8、16和25小时进行测量。超滤速率为30至60毫升/分钟。所有患者均观察到动脉压（舒张压和平均压）稳定，总外周血管阻力恢复正常，且与血液滤过治疗前的中心血流动力学状态无关。具有主要升压作用的儿茶酚胺剂量减少。心肺氧输送和消耗的综合参数未改变。在多器官功能衰竭综合征患者所采用的强化治疗措施中加入VVHF，9例（56%）患者取得了满意的效果。7例（44%）患者在VVHF后的不同时期死亡，其中6例发生休克。
