Bobrinskaia I G, Tishkov E A, Bukaev O B, Kapunov S V, Konstantinov V V, Smolenenkova S V
Anesteziol Reanimatol. 1998 Nov-Dec(6):58-62.
Effects of hemofiltration (HF) on central hemodynamics and oxygen transport are studied in 35 patients with surgical sepsis and multiple organ failure. HF is paralleled by development of hypovolemia and decrease of myocardial contractility, determining a decrease in cardiac output and oxygen transport. As a result, oxygen utilization by tissues decreases and hypoxia progresses. The only compensatory mechanism of oxygen supply in such patients is maintenance of cardiac output, which should be borne in mind when carrying out HF.
对35例外科脓毒症和多器官功能衰竭患者研究了血液滤过(HF)对中心血流动力学和氧输送的影响。血液滤过伴随着血容量减少和心肌收缩力下降,导致心输出量和氧输送降低。结果,组织对氧的利用减少,缺氧加重。这类患者唯一的氧供应代偿机制是维持心输出量,在进行血液滤过时应牢记这一点。