Luzhnikov E A, Dagaev V N, Gol'dfarb Iu S, Il'iashenko K K
Anesteziol Reanimatol. 1995 Jan-Feb(1):9-16.
Computers offer new possibilities for scientifically-based analysis of emergency states in toxicological patients and for improvement of treatment of such patients. Toxicometric assessment of the quantitative effect of toxic compounds using computer programs BMDP, SSP, and SAS with probit analysis, factor, cluster, and other types of analysis is particularly valuable. Such an approach permits a most objective assessment of the toxicokinetics and toxicodynamics of poisons, helps single out the priority trends in research with due consideration for the type of toxin which caused poisoning, changes in clinical laboratory parameters, etc. Computer support may be indispensable during the use of artificial (dialysis sorption) methods of detoxication of the organism.
计算机为基于科学的毒理学患者紧急状态分析以及此类患者治疗的改善提供了新的可能性。使用BMDP、SSP和SAS等计算机程序并结合概率分析、因子分析、聚类分析及其他类型的分析，对有毒化合物的定量效应进行毒物测定评估尤为重要。这种方法能够最客观地评估毒物的毒代动力学和毒效动力学，有助于在充分考虑引起中毒的毒素类型、临床实验室参数变化等因素的情况下，确定研究的优先方向。在使用机体人工（透析吸附）解毒方法时，计算机支持可能必不可少。
