Hrabovsky E, Jones B
Am J Dis Child. 1979 Jan;133(1):73-5. doi: 10.1001/archpedi.1979.02130010079015.
Congenital neuroblastoma is a well-recognized entity with a very favorable prognosis for tumor cure. However, a newborn with neurologic deficit owing to intraspinal extension of this tumor is very unusual. Eleven such cases in the world literature are reviewed, and an additional case of a new born with paralysis and a neurogenic bladder at birth is presented in detail. The prognosis for tumor cure is excellent regardless of the mode of therapy used. Because of this fact, treatment should include safe surgical decompression and chemotherapy only. The outlook for the return of normal neurologic function is poor.
先天性神经母细胞瘤是一种公认的疾病实体,其肿瘤治愈预后非常良好。然而,因该肿瘤脊髓内扩展导致神经功能缺损的新生儿非常罕见。本文回顾了世界文献中的11例此类病例,并详细介绍了另外1例出生时即伴有瘫痪和神经源性膀胱的新生儿病例。无论采用何种治疗方式,肿瘤治愈的预后都非常好。基于这一事实,治疗应仅包括安全的手术减压和化疗。神经功能恢复正常的前景不佳。