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重组凝血因子VIIa在一名接受手术的获得性甲型血友病患者中的应用。

The use of recombinant factor VIIa in a patient with acquired haemophilia A undergoing surgery.

作者信息

Doughty H A, Northeast A, Sklair L, Roques T, Young A E, Savidge G F, Hunt B J

机构信息

Haemophilia Centre, St Thomas' Hospital, London, UK.

出版信息

Blood Coagul Fibrinolysis. 1995 Apr;6(2):125-8. doi: 10.1097/00001721-199504000-00006.

DOI:10.1097/00001721-199504000-00006
PMID:7605877
Abstract

An elderly woman with acquired haemophilia A secondary to a monoclonal gammopathy, required elective surgery for a parotid tumour but was unable to tolerate conventional treatment. Recombinant activated factor VII (rVIIa) was used successfully to cover a biopsy and then subsequent resection of the tumour. The use of rVIIa in the management of acquired inhibitors is discussed.

摘要

一名患有继发于单克隆丙种球蛋白病的获得性血友病A的老年女性，因腮腺肿瘤需要择期手术，但无法耐受传统治疗。重组活化因子VII（rVIIa）成功用于覆盖活检以及随后的肿瘤切除。本文讨论了rVIIa在获得性抑制剂管理中的应用。

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