Tsuyuoka R, Takahashi T, Sasaki Y, Nakamura K, Fukumoto M, Kurisu Y, Tsubakimori K, Shioi K, Nakao K
Department of Medicine, Kyoto University, Faculty of Medicine.
Intern Med. 1995 Apr;34(4):251-4. doi: 10.2169/internalmedicine.34.251.
A 76-year-old female was diagnosed as having primary plasma cell leukemia (PCL), based on abundant atypical plasma cells in the circulation and bone marrow, monoclonal kappa light chain in the serum and urine, the immunophenotype of the plasma cells and the lack of preceding multiple myeloma. The patient was treated with melphalan and prednisolone (MP), and complete remission (CR) was achieved; this was maintained for 28 months. The duration of CR in this patient appears to be the longest of those reported in well-documented primary PCL patients who have been treated with MP chemotherapy.
一名76岁女性，根据循环血液和骨髓中存在大量非典型浆细胞、血清和尿液中的单克隆κ轻链、浆细胞的免疫表型以及无先前多发性骨髓瘤病史，被诊断为原发性浆细胞白血病（PCL）。该患者接受了美法仑和泼尼松（MP）治疗，并实现了完全缓解（CR）；这种缓解状态维持了28个月。在接受MP化疗的原发性PCL患者中，该患者的CR持续时间似乎是有充分记录的患者中最长的。
