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使用乳内动脉移植物进行再次冠状动脉手术的风险、益处及结果。

Risks, benefits and results of reoperative coronary surgery with internal mammary grafts.

作者信息

Christenson J T, Velebit V, Maurice J, Simonet F, Schmuziger M

机构信息

Cardiovascular Unit, Hôpital de la Tour, Meyrin-Geneva and Clinique de Genolier, Switzerland.

出版信息

Cardiovasc Surg. 1995 Apr;3(2):163-9. doi: 10.1016/0967-2109(95)90888-c.

DOI:10.1016/0967-2109(95)90888-c
PMID:7606400
Abstract

To determine the effect of a prior internal mammary artery graft on coronary artery bypass reoperation, experience with 189 consecutive patients who underwent such surgery was reviewed. Some 147 patients (group I) received only saphenous vein grafts at the primary coronary bypass surgery (CABG) and 42 (group II) received at least one IMA graft at the primary CABG. There were no differences in preoperative patient characteristics or operative data between the groups. Significantly more redo CABG 0-5 years after the initial operation was seen in group II compared with that in group I, indicating inadequate first operation or technical difficulties. In group II a larger proportion of the patients had patent grafts at redo (52.4% versus 34.7%). There were no entry injuries to the grafts or the heart in either group. No operative mortality was encountered in group II, while seven patients in group I died (P < 0.05). Group II had more pneumonia (P < 0.01) and re-exploration for bleeding (P < 0.001) than group I. However, the overall postoperative morbidity in group II patients was less than in group I, though not statistically significant. When comparing patients with an occluded internal mammary artery graft at redo (group A) with those who had a patent internal mammary artery graft (group B) there were no statistically significant differences in patient characteristics and preoperative patient profile, even though group B patients showed a trend towards a better preoperative cardiac profile. A mean of 2.4 grafts/patient were performed in group B compared with 4.0 in group A (P < 0.01). Other operative parameters did not differ between the groups.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为确定既往乳内动脉移植对冠状动脉搭桥再手术的影响,回顾了189例连续接受此类手术患者的经验。约147例患者(I组)在初次冠状动脉搭桥手术(CABG)时仅接受了大隐静脉移植,42例(II组)在初次CABG时接受了至少1根乳内动脉移植。两组患者术前特征或手术数据无差异。与I组相比,II组在初次手术后0至5年进行再次CABG的患者明显更多,提示初次手术不充分或存在技术困难。II组在再次手术时有更大比例的患者移植血管通畅(52.4%对34.7%)。两组均未发生移植血管或心脏的入口损伤。II组未发生手术死亡,而I组有7例患者死亡(P<0.05)。II组的肺炎(P<0.01)和因出血再次探查(P<0.001)比I组更多。然而,II组患者的总体术后发病率低于I组,尽管无统计学意义。将再次手术时乳内动脉移植血管闭塞的患者(A组)与乳内动脉移植血管通畅的患者(B组)进行比较,患者特征和术前情况无统计学显著差异,尽管B组患者术前心脏情况有更好的趋势。B组患者平均每位进行2.4根移植血管,而A组为4.0根(P<0.01)。两组间其他手术参数无差异。(摘要截短于250词)

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