Dunkman W B
Cardilogy Section 111C, Veterans Affairs Medical Center, Philadephia, PA 19104, USA.
J Cardiovasc Risk. 1995 Apr;2(2):107-17.
The incidence of thromboembolic events in unselected patients with class II-III congestive heart failure is 1.6-3.5% per year. Marked limitation of exercise capacity and the presence of echocardiographic left ventricular thrombus appear to be associated with an increased risk of thromboembolism. Several studies have reported that anticoagulant therapy does not eliminate the occurrence of thromboembolism. Because the benefit and risks of anticoagulant therapy in patients with congestive heart failure have not been examined in controlled studies, it is difficult to make well-founded recommendations.
在未经挑选的II-III级充血性心力衰竭患者中，血栓栓塞事件的发生率为每年1.6%-3.5%。运动能力明显受限以及超声心动图显示左心室血栓的存在似乎与血栓栓塞风险增加有关。几项研究报告称，抗凝治疗并不能消除血栓栓塞的发生。由于尚未在对照研究中考察充血性心力衰竭患者抗凝治疗的益处和风险，因此很难给出有充分依据的建议。
