通过荧光原位杂交将人类CREBBP（CREB结合蛋白）定位到16p13.3。
Localization of human CREBBP (CREB binding protein) to 16p13.3 by fluorescence in situ hybridization.
作者信息
Chen X N, Korenberg J R
机构信息
Medical Genetics Birth Defects Center, Ahmanson Department of Pediatrics, Cedars-Sinai Research Institute, UCLA, USA.
出版信息
Cytogenet Cell Genet. 1995;71(1):56-7. doi: 10.1159/000134062.
PMID:7606928
Abstract
Human and mouse cDNAs for a 265-kDa protein which binds specifically to phosphorylated cAMP-response element binding protein (CREB), have recently been isolated. A cDNA probe for the mouse CREB binding protein was used to localize this gene (CREBBP) to human chromosome 16p13.3 by fluorescence in situ hybridization (FISH).
摘要
最近已分离出与磷酸化的环磷酸腺苷反应元件结合蛋白（CREB）特异性结合的265 kDa蛋白质的人和小鼠cDNA。通过荧光原位杂交（FISH），使用小鼠CREB结合蛋白的cDNA探针将该基因（CREBBP）定位到人类染色体16p13.3上。
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