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[海德堡重症监护病房评分。一种用于记录手术重症监护患者治疗过程和评估预后的计算机辅助评分系统的开发]

[The Heidelberg Intensive Care Unit Score. Development of a computer-assisted scoring system for documentation of treatment course and assessment of prognosis in surgical intensive care patients].

作者信息

Foitzik T, Holle R, Schall R, Moesta T, Buhr H J, Herfarth C

机构信息

Chirurgische Klinik, Universität Heidelberg.

出版信息

Chirurg. 1995 May;66(5):513-8.

PMID:7607015
Abstract

Existing scoring systems have failed to reflect the pathophysiological changes during ICU therapy, and do not provide reliable criteria for the prediction of outcome in surgical patients. The aim of the present project was to establish a comprehensive scoring system for daily evaluation of physiological parameters and therapeutic interventions in a surgical intensive care unit, and to identify score patterns in the course of ICU treatment to be used for prospective clinical decisions. In a prospective study of 123 consecutive patients who required intensive care for more than two consecutive days we documented 10 physiological parameters and a set of 14 therapeutic interventions on a daily basis over a total of 1274 days. Evaluation of the new scoring system, called the Heidelberg Intensive Ward Score (HDWS), included comparison with APACHE II and a set of unfavorable HDWS-patterns at different time points during ICU treatment. All variables were implemented into a notebook computer to be used at bedside. Neither HDWS nor APACHE II obtained on admission differentiated between survivors and non-survivors. In contrast, scores of non survivors were significantly higher than scores of survivors at day 7. At that point, HDWS was superior to APACHE II with respect to the predictive power as assessed by receiver operator characteristic curves. No patient who fulfilled all four unfavorable HDWS-patterns during the first week of ICU treatment survived (but these were only two patients). We conclude that the limited power of scores obtained on admission to predict outcome in surgical patients may be improved by trend analysis of scores over time which also take into account the patients' response to therapy.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

现有的评分系统未能反映重症监护病房(ICU)治疗期间的病理生理变化,也未为预测外科患者的预后提供可靠标准。本项目的目的是建立一个综合评分系统,用于日常评估外科重症监护病房患者的生理参数和治疗干预措施,并识别ICU治疗过程中的评分模式,以用于前瞻性临床决策。在一项对123例连续需要重症监护超过两天的患者的前瞻性研究中,我们在总共1274天的时间里每天记录10项生理参数和一组14项治疗干预措施。对新的评分系统——海德堡重症监护病房评分(HDWS)的评估,包括与急性生理与慢性健康状况评分系统II(APACHE II)进行比较,以及在ICU治疗期间不同时间点的一组不良HDWS模式。所有变量都输入到一台笔记本电脑中,以便在床边使用。入院时获得的HDWS和APACHE II评分均无法区分幸存者和非幸存者。相比之下,在第7天时,非幸存者的评分显著高于幸存者。此时,通过受试者工作特征曲线评估,HDWS在预测能力方面优于APACHE II。在ICU治疗的第一周内符合所有四项不良HDWS模式的患者无一存活(但只有两名患者)。我们得出结论,入院时获得的评分预测外科患者预后的能力有限,通过对评分随时间的趋势分析(同时考虑患者对治疗的反应)可能会有所改善。(摘要截短于250字)

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