Vaĭsman N Ia, Zakharov I K
Genetika. 1995 Mar;31(3):358-62.
Gene Mosaic (Mos) of chromosome 3 of Drosophila melanogaster was located by means of dominant markers Ly, Sb, and Dr. This gene was shown to be located between Ly and Sb in the centromeric region (45-50 map units). An analysis of interaction between Mos and mwh genes in cis and trans-heterozygotes showed a significant effect of the Mos gene on mutability (recombinogenesis) of chromosome mwh in somatic cells. In the cis heterozygote mwh Mos/++, the frequency of small mutant clones on wings of flies increased. In mwh/Mos heterozygotes, the Mos gene caused a significant reduction of dorsocentral and scutellar bristles (78% in mwh/Mos, 85% in mwh +/+ Mos, and 98% in mwh Mos/mwh +).
利用显性标记Ly、Sb和Dr定位了黑腹果蝇3号染色体上的基因镶嵌体（Mos）。该基因位于着丝粒区域（45 - 50个图距单位）的Ly和Sb之间。对顺式和反式杂合子中Mos和mwh基因之间相互作用的分析表明，Mos基因对体细胞中mwh染色体的突变性（重组发生）有显著影响。在顺式杂合子mwh Mos/++中，果蝇翅膀上小突变克隆的频率增加。在mwh/Mos杂合子中，Mos基因导致背中鬃和小盾片刚毛显著减少（mwh/Mos中减少78%，mwh +/+ Mos中减少85%，mwh Mos/mwh +中减少98%）。
