Ogami K, Shimada Y, Sohma Y, Akahori H, Kato T, Kawamura K, Miyazaki H
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd., Gunma, Japan.
Gene. 1995 Jun 9;158(2):309-10. doi: 10.1016/0378-1119(95)00125-p.
Overlapping cDNA clones encoding rat thrombopoietin (TPO) were isolated from liver-derived cell line cDNA libraries and the nucleotide sequences were determined. The deduced 326-amino-acid rat TPO showed significant homology to the known TPO of other species, especially in the N-terminal sequence.
从大鼠肝脏来源的细胞系cDNA文库中分离出编码大鼠血小板生成素（TPO）的重叠cDNA克隆，并测定了其核苷酸序列。推导的由326个氨基酸组成的大鼠TPO与其他物种已知的TPO具有显著的同源性，尤其是在N端序列。
