Aoyagi S, Hiney K M, Baker D H
Department of Animal Sciences, University of Illinois, Urbana 61801, USA.
J Anim Sci. 1995 Mar;73(3):793-8. doi: 10.2527/1995.733793x.
Four chick experiments were conducted to investigate possible explanations for why Cu bioavailability in pork liver is zero. One possible explanation was that pork liver contains compounds, such as Zn, that directly or indirectly inhibit Cu utilization. It has also been suggested that sex differences may influence Cu bioavailability. The effect of freeze-dried (FD) pork liver from gilts vs barrows was first examined. Neither FD gilt liver nor FD barrow liver provided any bioavailable Cu to chicks. The effect of sex of the chicks used in the assay (i.e., male chicks vs female chicks) was also examined, but there were no sex-dependent differences (P > .10) in the slopes of the standard curve generated by added Cu from CuSO4 or in the responses to added FD pork liver. Based on bone Zn uptake, Zn bioavailability in FD barrow liver and FD gilt liver was not different (P > .04) from that in ZnSO4, but Fe bioavailability (hemoglobin repletion assay) was approximately 40% (P < .05) of that in FeSO4 in both FD gilt liver and FD barrow liver.
进行了四项雏鸡实验，以探究猪肝中铜生物利用率为零的可能原因。一种可能的解释是，猪肝含有锌等化合物，这些化合物直接或间接抑制铜的利用。也有人提出性别差异可能会影响铜的生物利用率。首先研究了来自后备母猪和阉公猪的冻干（FD）猪肝的影响。FD后备母猪肝脏和FD阉公猪肝脏均未向雏鸡提供任何可生物利用的铜。还研究了测定中所用雏鸡的性别（即雄性雏鸡与雌性雏鸡）的影响，但在由硫酸铜添加的铜生成的标准曲线斜率或对添加的FD猪肝的反应方面，没有性别依赖性差异（P>.10）。基于骨骼锌摄取量，FD阉公猪肝脏和FD后备母猪肝脏中的锌生物利用率与硫酸锌中的锌生物利用率无差异（P>.04），但在FD后备母猪肝脏和FD阉公猪肝脏中，铁生物利用率（血红蛋白补充测定）约为硫酸亚铁中铁生物利用率的40%（P<.05）。
