Masuyama T, Yamaguchi S, Tsurumaru T, Ikeda K, Yoshimura N
Department of Anesthesiology and Critical Care Medicine, Kagoshima University School of Medicine.
Masui. 1995 May;44(5):660-7.
Differences of blood pressures measured directly at the radial and dorsalis pedis arteries were compared in relation to the sites of the epidural puncture. Epidural catheters were inserted at C7-Th9 in the upper (U) group (n = 7), and at L1-4 in lower (L) group (n = 7). In the awake, unanesthetized state, the systolic, mean and diastolic radial-to-dorsal pressure differences (DR-D) were -21.9 +/- 11.0 mmHg (mean +/- SD), 0.9 +/- 1.1 mmHg and 2.1 +/- 2.1 mmHg respectively. Following epidural infusion of mepivacaine, the DR-D values shifted to the negative direction in the U group, and to the positive direction in the L group. Epidural anesthesia had little effect on the DR-D changes during general anesthesia; however, it affected significantly the mean pressure DR-D as well as the systolic pressure DR-D during the periods of preinduction and postemergence. The maximum change in systolic pressure DR-D values was from -19.4 to -36.3 mmHg in a patient of the U group and from -15.6 to 45.4 mmHg in a patient of the L group. The maximum change in mean pressure DR-D values was from 0.0 to -7.4 mmHg in the U group and from 2.1 to 18.3 mmHg in the L group. The DR-D values had significant negative correlations with the deep temperature (palm to sole) differences; the correlation coefficients were: systolic, r = -0.50; mean, r = -0.50; and diastolic, r = -0.41. These results demonstrated that epidural anesthesia changed the physiological central-to-peripheral pressure gradients, probably by influencing the regional peripheral vascular resistance.
比较了在桡动脉和足背动脉直接测量的血压差异与硬膜外穿刺部位的关系。在上部(U)组(n = 7)中,硬膜外导管插入C7 - Th9,在下部(L)组(n = 7)中插入L1 - 4。在清醒、未麻醉状态下,收缩压、平均压和舒张压的桡动脉与背动脉压力差(DR - D)分别为-21.9±11.0 mmHg(平均值±标准差)、0.9±1.1 mmHg和2.1±2.1 mmHg。硬膜外注入甲哌卡因后,U组的DR - D值向负方向移动,L组向正方向移动。硬膜外麻醉对全身麻醉期间的DR - D变化影响较小;然而,它在诱导前和苏醒后期间对平均压DR - D以及收缩压DR - D有显著影响。U组一名患者的收缩压DR - D值最大变化为从-19.4至-36.3 mmHg,L组一名患者为从-15.6至45.4 mmHg。U组平均压DR - D值最大变化为从0.0至-7.4 mmHg,L组为从2.1至18.3 mmHg。DR - D值与深部温度(手掌至足底)差异呈显著负相关;相关系数分别为:收缩压,r = -0.50;平均压,r = -0.50;舒张压,r = -0.41。这些结果表明,硬膜外麻醉可能通过影响局部外周血管阻力改变了生理上的中心至外周压力梯度。