Tokuno T, Nakazawa K, Yoshida S, Matsumoto S, Shingu T, Sato S, Ban S, Yamamoto T
Department of Neurosurgery, Kobe City General Hospital.
No Shinkei Geka. 1995 Jun;23(6):497-501.
Ten cases of primary oculomotor nerve palsy due to head injury are presented. All ten patients had a dilated, non reactive pupil. Seven had complete oculomotor palsy. Two had partial extraocular palsy or blepharoptosis and one had neither extraocular palsy nor blepharoptosis. The initial ophthalmoplegia was recognized immediately after trauma. Nine patients had severely impaired consciousness on admission, but eight patients recovered fully within two months after the traumatic event, while one patient remained disoriented. Emergency CT scan on admission showed mass lesions in no patients except one who had a hematoma measuring 3 cm in the frontal lobe, but had no herniation sign. Patients with complete oculomotor palsy had a high incidence of traumatic SAH (71%) or skull fracture (57%). Recovery from third nerve palsy was not so good. The follow-up period extended from 3 months to 18 months. Of the 10 patients, none recovered completely from third nerve palsy. The prognoses of blepharoptosis, external ophthalmoplegia and internal ophthalmoplegia were analyzed separately. The recovery rates were 78%, 44% and 20%, respectively, the internal ophthalmoplegia showing poorest recovery. We discuss the mechanism of direct injury to the oculomotor nerve.
本文报告了10例因头部受伤导致的原发性动眼神经麻痹病例。所有10例患者均有瞳孔散大且无反应。7例出现完全性动眼神经麻痹。2例有部分眼外肌麻痹或上睑下垂,1例既无眼外肌麻痹也无上睑下垂。最初的眼肌麻痹在创伤后立即被发现。9例患者入院时意识严重受损,但8例患者在创伤事件后两个月内完全康复,而1例患者仍有定向障碍。入院时的急诊CT扫描显示,除1例额叶有3 cm血肿但无疝出迹象的患者外,其他患者均无占位性病变。完全性动眼神经麻痹患者创伤性蛛网膜下腔出血(71%)或颅骨骨折(57%)的发生率较高。动眼神经麻痹的恢复情况不太理想。随访期从3个月延长至18个月。10例患者中,无1例动眼神经麻痹完全恢复。分别分析了上睑下垂、外眼肌麻痹和内眼肌麻痹的预后。恢复率分别为78%、44%和20%,内眼肌麻痹的恢复情况最差。我们讨论了动眼神经直接损伤的机制。