载脂蛋白E等位基因而非载脂蛋白B或载脂蛋白AI/CIII等位基因与晚发型家族性阿尔茨海默病相关。
Apolipoprotein E alleles but neither apolipoprotein B nor apolipoprotein AI/CIII alleles are associated with late onset, familial Alzheimer's disease.
作者信息
Houlden H, Crook R, Duff K, Hutton M, Collinge J, Roques P, Rossor M, Hardy J
机构信息
Suncoast Alzheimer's Disease Labs., Departments of Psychiatry, Pharmacology, Neurology and Biochemistry, University of South Florida, Tampa 33613, USA.
出版信息
Neurosci Lett. 1995 Mar 31;188(3):202-4. doi: 10.1016/0304-3940(95)11422-s.
PMID:7609909
Abstract
The possibility of a genetic association between late onset, familial Alzheimer's disease and alleles at the apolipoprotein B and AI/CIII loci have been examined. In contrast to the genetic association with the apolipoprotein E locus, no evidence for genetic associations to these loci was found.
摘要
研究了晚发型家族性阿尔茨海默病与载脂蛋白B及AI/CIII基因座上等位基因之间存在遗传关联的可能性。与载脂蛋白E基因座的遗传关联不同，未发现与这些基因座存在遗传关联的证据。
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