Baba H, Maezawa Y, Furusawa N, Imura S, Tomita K
Department of Orthopaedic Surgery, Fukui Medical School, Japan.
Paraplegia. 1995 Apr;33(4):219-23. doi: 10.1038/sc.1995.49.
Our report concerns five patients who underwent lumbar decompressive surgery for cauda equina syndrome and radiculopathy secondary to degenerative stenosis associated with calcium deposition in the ligamentum flavum. The resected ligamentum flavum showed diffuse to massive calcium crystal deposition with a histologically marked degeneration in the elastic fibres. Energy dispensive radiographic microanalysis confirmed the crystal to be calcium pyrophosphate dihydrate in all patients, hydroxyapatite mixed in three and calcium orthophosphate mixed in one. The deposition appeared to be a change that is associated with the degenerative process in the ligament and, in some cases having marked deposition in a localised event, it causes or aggravates the neurological symptoms.
我们的报告涉及五名因马尾综合征和继发于退行性狭窄并伴有黄韧带钙沉积的神经根病而接受腰椎减压手术的患者。切除的黄韧带显示出弥漫性至大量的钙晶体沉积，弹性纤维有明显的组织学退变。能量色散射线显微分析证实，所有患者的晶体均为二水焦磷酸钙，三名患者混合有羟基磷灰石，一名患者混合有正磷酸钙。这种沉积似乎是一种与韧带退变过程相关的变化，在某些情况下，局部有明显沉积时，会导致或加重神经症状。
