Sciacca A, Betta P, Cilauro S, Saporito A, Tina L G
Clinica Pediatrica I, Università di Catania, Italia.
Pediatr Med Chir. 1995 Mar-Apr;17(2):173-5.
Systemic Candida A. infections are increasing in Neonatal Intensive Care Units. For many years, Amphotericin B, alone or in combination with 5-fluorocytosine, have been used. Recently a search for new and less toxic drugs has been started. In this study we report the case of hepatic candidosis in a preterm newborn. The patient has been treated with itraconazole, an oral antifungal agent with broad spectrum activity. Its tolerance has been good. No severe side effects were observed and biochemical parameters showed no consistent drug induced effects.
全身性白色念珠菌感染在新生儿重症监护病房中呈上升趋势。多年来，两性霉素B单独使用或与5-氟胞嘧啶联合使用。最近，人们开始寻找新的、毒性较小的药物。在本研究中，我们报告了一例早产新生儿肝念珠菌病的病例。该患者接受了伊曲康唑治疗，伊曲康唑是一种具有广谱活性的口服抗真菌剂。其耐受性良好。未观察到严重副作用，生化指标也未显示出一致的药物诱导效应。
