de Castro C C, de Barros N G, Campos Z M, Cerri G G
Division of Diagnostic Imaging, Heart Institute, Clinics Hospital of the Medical School, University of São Paulo, Brazil.
Radiol Clin North Am. 1995 Jul;33(4):753-69.
Tuberculosis of the central nervous system is still an important cause of death or significant neurologic disability. Prompt diagnosis and early treatment are extremely important to reduce its morbidity and mortality. The main forms of intracranial tuberculosis are represented by tuberculous meningitis, meningeal or parenchymal tuberculomas, and tuberculous abscess formation. Sequelae consist of hydrocephalus, calcifications, and areas of encephalomalacia. Less frequent manifestations include tuberculous osteitis of the skull and tuberculous otomastoiditis. Although MR imaging is in general somewhat more sensitive to the detection of cranial tuberculosis, CT is the diagnostic imaging mainstay in many clinical settings to demonstrate the various aspects of cranial tuberculosis on initial presentation and to monitor the evolution of the disease and response to therapy.
中枢神经系统结核仍然是导致死亡或严重神经功能残疾的重要原因。及时诊断和早期治疗对于降低其发病率和死亡率极为重要。颅内结核的主要形式表现为结核性脑膜炎、脑膜或实质结核瘤以及结核性脓肿形成。后遗症包括脑积水、钙化和脑软化区域。较少见的表现包括颅骨结核性骨炎和结核性耳乳突炎。尽管磁共振成像(MR成像)总体上对颅骨结核的检测更为敏感,但在许多临床情况下,计算机断层扫描(CT)是诊断成像的主要手段,用于在初次就诊时显示颅骨结核的各个方面,并监测疾病的进展以及对治疗的反应。