Nozaki H, Toyoda T, Takashima S, Urano T, Yamada K, Ryu M, Aoyagi T
Department of Internal Medicine, National Higashi-Saitama Hospital, Japan.
Kekkaku. 1992 May;67(5):383-92.
We have experienced 6 cases of intracranial tuberculosis since 1985. 2 cases were diagnosed as intracranial tuberculoma without tuberculous meningitis, and 4 cases were diagnosed as tuberculous meningitis. Brain CT showed intracranial tuberculomas in three of them, and showed cerebral infarcts in two cases, and showed hydrocephalus in two cases. Brain CT on intracranial tuberculosis showed various findings. In two cases with tuberculous meningitis, brain CT showed many tuberculomas with ringed or nodular enhancement appeared after adequate chemotherapy had been started. About 1 year later, a few tuberculomas were found with homogeneous enhancement and were enlarged while the chemotherapy was continued. But later they were reduced in size. The above facts may suggest that intracranial tuberculoma could appear and be enlarged on cranial CT in spite of adequate anti-tuberculous chemotherapy during a course of tuberculous meningitis. They also suggest that the continuation of adequate chemotherapy might be necessary to the treatment of intracranial tuberculomas.
自1985年以来,我们共收治6例颅内结核患者。其中2例诊断为无结核性脑膜炎的颅内结核瘤,4例诊断为结核性脑膜炎。脑部CT显示,其中3例有颅内结核瘤,2例有脑梗死,2例有脑积水。颅内结核的脑部CT表现多样。2例结核性脑膜炎患者在开始充分化疗后,脑部CT显示许多结核瘤出现环形或结节状强化。大约1年后,在继续化疗的过程中发现一些结核瘤呈均匀强化且增大,但随后体积缩小。上述情况可能提示,在结核性脑膜炎病程中,尽管进行了充分的抗结核化疗,颅内结核瘤仍可能在头颅CT上出现并增大。这也表明,持续进行充分化疗对颅内结核瘤的治疗可能是必要的。