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[蛋白胨刺激巨噬细胞生成对伯氏疟原虫感染小鼠实验的偶然影响]

[Casual influence of the stimulation of macrophage production by proteose-peptone, in the experimental infection of mice by Plasmodium berghei].

作者信息

Arantes S C, Braz L M, Amato Neto V

机构信息

Laboratório de Investigação Médica-Parasitologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo.

出版信息

Rev Hosp Clin Fac Med Sao Paulo. 1994 Nov-Dec;49(6):243-5.

PMID:7610336
Abstract

Proteose-peptone is a known powerful stimulator of macrophages. This stimulation was studied in an experimental malaria infection model, using Plasmodium berghei in mice. Parasitemia and mortality did not change in stimulated animals, and macrophage mobilization, contrary to other published papers, was not effective to increase either parasite levels in the blood or mortality.

摘要

蛋白胨是一种已知的巨噬细胞强力刺激剂。在使用伯氏疟原虫感染小鼠的实验性疟疾感染模型中对这种刺激作用进行了研究。在受到刺激的动物中,疟原虫血症和死亡率没有变化,而且与其他已发表论文的情况相反,巨噬细胞动员对于提高血液中的寄生虫水平或死亡率并无效果。

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