Akberov R F, Gorshkov A N
Vopr Onkol. 1994;40(7-12):346-9.
The study group included 200 patients, aged 24-70, with such precancerous lesions in gastric mucosa as epithelial dysplasia and intestinal metaplasia. The pathology was identified by roentgenoendoscopic examination of stomach wall lesions. Changes were followed up in 82 cases during periods of time ranging from 1 month to 5 years. Progression of dysplasia was registered in 20%, malignant conversion and cancer development occuring in 12% following moderate and grave dysplasia. A set of roentgeno-endoscopic signs of stomach wall lesions was identified, which provides efficient means for detection of said pathologies. Both morphological and roentgeno-endoscopic evidence should be considreed in identifying groups at risk. A time schedule is suggested for repeated examination during follow-up.
研究组包括200例年龄在24至70岁之间的患者，他们患有胃黏膜上皮发育异常和肠化生等癌前病变。通过对胃壁病变进行X线内镜检查来确定病理情况。对82例患者进行了1个月至5年不等时间的随访观察。发育异常进展的占20%，中度和重度发育异常后发生恶变和癌症的占12%。确定了一组胃壁病变的X线内镜征象，这为检测上述病变提供了有效的手段。在确定高危人群时应同时考虑形态学和X线内镜证据。建议制定随访期间重复检查的时间表。
