Andrea M, Dias O, Santos A
Department of Otolaryngology, Faculty of Medicine of Lisbon, Portugal.
Acta Otolaryngol. 1995 Mar;115(2):314-6. doi: 10.3109/00016489509139318.
Contact endoscopy allows an in vivo and in situ study of the superficial layers of the vocal cord epithelium. This technique offers access to some characteristics of the epithelium cells: dimension and shape of the nuclei, nucleus/cytoplasm ratio, keratosis, presence of nucleolus, mitosis and koylocites. Contact endoscopy was performed during microlaryngoscopies in 92 patients with benign, pre-malign and malign pathology of the vocal cords. Systematic confrontation with pathological examination and laryngectomy specimens studied by histology and electron microscopy were used to improve the interpretation of contact endoscopy findings. Based on this correlation it has been possible to analyse the transition of the squamous and ciliated epithelium of the vocal cord as well as to delineate some pathological patterns, e.g. chronic laryngitis, keratosis, dysplasia, tumor and papilloma.
接触式内镜检查可对声带上皮表层进行体内和原位研究。该技术能够观察到上皮细胞的一些特征：细胞核的大小和形状、核质比、角化、核仁的存在、有丝分裂和杯状细胞。对92例患有声带良性、癌前和恶性病变的患者在显微喉镜检查期间进行了接触式内镜检查。通过与病理检查以及经组织学和电子显微镜研究的喉切除术标本进行系统对比，以改进对接触式内镜检查结果的解读。基于这种相关性，得以分析声带鳞状上皮和纤毛上皮的转变，并勾勒出一些病理模式，如慢性喉炎、角化、发育异常、肿瘤和乳头状瘤。
