Ellsworth J, Marks M I, Vose A
Can Med Assoc J. 1979 Jan 20;120(2):155-8.
Forty-four cases of meningococcal meningitis in children at one hospital between 1971 and 1975 inclusive were studied to document the course and complications of this disease in children in the current therapeutic era. The mortality was 5%. Of the 41 survivors 76% were healthy 1 to 5 years after the episode of meningitis. Permanent severe sequelae (facial palsy, optic atrophy and ptosis) were seen in three (7%) of the survivors, and mild hearing loss, hyperactivity and nervousness were noted in seven (17%). Electroencephalography was not useful in determining management or prognosis. Both the mortality and the frequency of early and late complications among the survivors were lower than those reported from earlier studies.
为记录当前治疗时代儿童脑膜炎球菌性脑膜炎的病程及并发症,对一家医院在1971年至1975年(含)期间收治的44例儿童脑膜炎球菌性脑膜炎病例进行了研究。死亡率为5%。在41名幸存者中,76%在脑膜炎发作后1至5年健康状况良好。3名(7%)幸存者出现永久性严重后遗症(面瘫、视神经萎缩和上睑下垂),7名(17%)存在轻度听力损失、多动和神经质。脑电图检查对确定治疗方案或预后并无帮助。幸存者中的死亡率以及早期和晚期并发症的发生率均低于早期研究报告的水平。