Bach J R
Department of Physical Medicine and Rehabilitation, University of Medicine & Dentistry of New Jersey-New Jersey Medical School, University Hospital, Newark 07103, USA.
Ann N Y Acad Sci. 1995 May 25;753:96-102. doi: 10.1111/j.1749-6632.1995.tb27535.x.
Post-poliomyelitis respiratory impairment is extremely common and entails considerable risk of morbidity and mortality. Respiratory muscle weakness is the primary etiological factor but post-poliomyelitis individuals (PPIs) also have a high incidence of scoliosis, obesity, sleep disordered breathing, and bulbar muscle dysfunction, all of which can add to the risk. One hundred forty-five PPIs were managed by noninvasive alternatives to intermittent positive pressure ventilation (IPPV) via an indwelling tracheostomy. When properly managed in this manner, acute respiratory failure requiring hospitalization, tracheal intubation, and bronchoscopies were avoided. Timely introduction of mouthpiece IPPV, nasal IPPV, manually and mechanically assisted coughing, and noninvasive blood gas monitoring in the home were the principal techniques used for optimizing quality of life and for avoiding complications.
脊髓灰质炎后呼吸功能障碍极为常见,且存在相当高的发病和死亡风险。呼吸肌无力是主要病因,但脊髓灰质炎后遗症患者(PPI)还存在脊柱侧弯、肥胖、睡眠呼吸紊乱和延髓肌功能障碍的高发病率,所有这些都会增加风险。145例PPI通过经留置气管造口术采用无创替代间歇性正压通气(IPPV)进行管理。以这种方式妥善管理时,避免了需要住院、气管插管和支气管镜检查的急性呼吸衰竭。在家中及时引入口含式IPPV、鼻IPPV、手动和机械辅助咳嗽以及无创血气监测是用于优化生活质量和避免并发症的主要技术。