刘易斯系统：肾移植中的新组织相容性抗原。
The Lewis system: New histocompatibility antigens in renal transplantation.
作者信息
Oriol R, Cartron J, Yvart J, Bedrossian J, Duboust A, Bariety J, Gluckman J C, Gagnadoux M F
出版信息
Lancet. 1978 Mar 18;1(8064):574-5. doi: 10.1016/s0140-6736(78)91024-3.
PMID:76120
Abstract
Lewis antigen types (Le, le) were retrospectively determined in 255 first-kidney-transplant recipients. Actuarial survival of grafts at two years was significantly lower in the le/le recipients than in the Le recipients. This indicates that mismatching of these antigens contributes to rejection of kidney transplants. The effects of mismatching for the Lewis and HLA antigen systems seemed to be additive.
摘要
对255例首次肾移植受者进行回顾性Lewis抗原分型（Le、le）。le/le型受者的移植物2年预期存活率显著低于Le型受者。这表明这些抗原不匹配会导致肾移植排斥反应。Lewis抗原系统和HLA抗原系统不匹配的影响似乎具有累加性。
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