Gudmundsson K, Kristleifsson G, Theodors A, Holbrook W P
Department of Medicine, City Hospital, University of Iceland, Reykjavik.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Feb;79(2):185-9. doi: 10.1016/s1079-2104(05)80280-x.
To obtain information on the connection between tooth erosion and acid gastroesophageal reflux, 14 patients (mean age, 15.7 years) with tooth erosion were investigated with simultaneous 24-hour pH monitoring in the esophagus and the oral cavity. Salivary parameters were also investigated in a larger group of 62 erosion patients (mean age, 21 years) and compared with a group of 50 controls (mean age, 28 years). No changes in oral pH were observed in a total of 339 acid reflux episodes, not even in long supine reflux episodes. Extended periods of lowered intra-oral pH to the level of 4 to 5 were observed but not connected with gastroesophageal reflux episodes. Significantly more (p < 0.001) erosion patients (34 of 62) had low salivary buffer capacity compared with controls (10 of 50).
为获取有关牙齿侵蚀与酸性胃食管反流之间联系的信息,对14名患有牙齿侵蚀的患者(平均年龄15.7岁)进行了研究,同时对食管和口腔进行24小时pH监测。还对62名侵蚀患者(平均年龄21岁)的更大群体进行了唾液参数研究,并与50名对照组(平均年龄28岁)进行了比较。在总共339次酸反流发作中,未观察到口腔pH值变化,即使在长时间仰卧位反流发作中也是如此。观察到口腔内pH值长时间降至4至5的水平,但与胃食管反流发作无关。与对照组(50名中的10名)相比,侵蚀患者(62名中的34名)唾液缓冲能力低的情况明显更多(p < 0.001)。