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髋臼翻修术中的颗粒状同种异体骨移植

Morselized homologous grafts in revision arthroplasty of the acetabulum.

作者信息

Herzog R, Morscher E

机构信息

Department of Orthopaedic Surgery, University, Basle, Switzerland.

出版信息

Chir Organi Mov. 1994 Oct-Dec;79(4):371-8.

PMID:7614878
Abstract

Because they show fairly good short- and mid-term results frozen, morselized homologous bone grafts have become very popular in acetabular reconstruction after failed total hip arthroplasty. Graft integration proceeds uneventfully. However, very little is known about its longevity. From 1980 to 1984 we performed 121 acetabular revisions in cases with contained bone defects utilizing homologous bone graft and a cementless non-coated or hydroxyapatite coated HDPE cup. At the end of 1991 (7 to 11 years after the operation), 43 patients (35%) were available for review. 41 patients (34% had died, 19 patients (16%) were lost to follow-up. In 18 patients (15%), the cups had been revised because of aseptic loosening. The Harris Hip Score showed 50% good to excellent results. Cups inserted after grafting of cystic defects showed almost no migration. However when cavity defects were filled with large bone grafts (n = 23), slow continuous cup migration and progressive graft resorption over time was observed. Due to this continuous resorption, we conclude, that morselized bone grafts do not guarantee an ever lasting inert interface. Once the non-coated HDPE cup is in contact with the autogenous host bed, bone osteolysis occurs and loosening proceeds. Cementless porous coated cups with morselized allografts alone may be used in acetabular revision only when cystic defects are present. The surface of the cup has to be brought into contact with a well vascularized autochthonous pelvic bone in order to achieve stable fixation. Segmental and massive cavity defects can only be reconstructed with morselized allografts when protected from loading by supporting rings.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

由于冷冻的、碎块状同种异体骨移植显示出相当不错的短期和中期效果,在全髋关节置换失败后的髋臼重建中已变得非常流行。移植骨整合过程顺利。然而,关于其长期效果却知之甚少。1980年至1984年,我们对121例存在包容性骨缺损的髋臼翻修病例使用了同种异体骨移植,并采用了无骨水泥非涂层或羟基磷灰石涂层的高密度聚乙烯(HDPE)杯。到1991年底(手术后7至11年),43例患者(35%)可供复查。41例患者(34%)已死亡,19例患者(16%)失访。18例患者(15%)因无菌性松动而进行了髋臼杯翻修。Harris髋关节评分显示50%的结果为良好至优秀。囊性缺损植骨后植入的髋臼杯几乎没有移位。然而,当用大块骨移植填充腔隙性缺损时(n = 23),随着时间的推移,观察到髋臼杯缓慢持续移位和移植骨逐渐吸收。由于这种持续吸收,我们得出结论,碎块状骨移植不能保证有一个持久的惰性界面。一旦非涂层HDPE杯与自体宿主床接触,就会发生骨溶解并导致松动。仅当存在囊性缺损时,无骨水泥多孔涂层杯与碎块状同种异体骨移植可单独用于髋臼翻修。髋臼杯表面必须与血运良好的自体骨盆骨接触,以实现稳定固定。节段性和大块腔隙性缺损只有在通过支撑环防止负重的情况下,才能用碎块状同种异体骨进行重建。(摘要截取自250词)

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