Peitsch W, Becker H D
Chirurg. 1979 Jan;50(1):33-8.
It has been postulated that resection therapy for peptic ulcer disease will result in an increased frequency of gastric stump cancer depending on the ulcer type and type of operation (Billroth I, Billroth II, gastroenterostomy). However, an extensive review of the literature shows that after Billroth II resection for gastric ulcer without enteroanastomosis the frequency of primary gastric stump cancer is not greater than in the case of medically treated benign gastric ulcers. The frequency of cancer of the gastric stump seems lower after resection for duodenal ulcer disease. It is possible that the combination of the Billroth II resection with an enteroanastomosis decreases the frequency of cancer of the gastric remnant. Clinical and experimental studies do not allow final statements on cancer frequency after Billroth I resection or simple gastroenterostomy.
据推测,消化性溃疡疾病的切除疗法会使胃残端癌的发生率增加,这取决于溃疡类型和手术方式(毕罗一式、毕罗二式、胃肠吻合术)。然而,对文献的广泛回顾表明,在无肠吻合术的情况下对胃溃疡进行毕罗二式切除后,原发性胃残端癌的发生率并不高于接受药物治疗的良性胃溃疡。十二指肠溃疡疾病切除术后胃残端癌的发生率似乎较低。毕罗二式切除与肠吻合术相结合可能会降低胃残余癌的发生率。临床和实验研究无法对毕罗一式切除或单纯胃肠吻合术后的癌症发生率作出最终论断。