一名系统性红斑狼疮患者出现获得性蛋白S缺乏症，导致视网膜中央静脉血栓形成。
Acquired protein S deficiency in a patient with systemic lupus erythematosus causing central retinal vein thrombosis.
作者信息
Prince H M, Thurlow P J, Buchanan R C, Ibrahim K M, Neeson P J
机构信息
Department of Haematology, Austin Hospital, Heidelberg, Victoria, Australia.
出版信息
J Clin Pathol. 1995 Apr;48(4):387-9. doi: 10.1136/jcp.48.4.387.
Abstract
A 16 year old girl with systemic lupus erythematosus (SLE) developed the rare complication of central retinal vein occlusion. Although classically a disease of older patients, it has been recognised in association with SLE but only in the presence of the lupus anticoagulant or antiphospholipid antibodies. The thrombosis occurred when free protein S concentrations were transiently reduced and there was no family history or other known causes of reduced protein S concentrations. No other prothrombotic risk factors were present.
摘要
一名16岁的系统性红斑狼疮（SLE）女孩出现了视网膜中央静脉阻塞这一罕见并发症。虽然视网膜中央静脉阻塞通常是老年患者的疾病，但它已被认为与SLE有关，不过仅在存在狼疮抗凝物或抗磷脂抗体的情况下。血栓形成发生在游离蛋白S浓度短暂降低时，且不存在家族病史或其他已知的蛋白S浓度降低原因。不存在其他血栓形成的危险因素。
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本文引用的文献
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Brief report: autoimmune protein S deficiency in a boy with severe thromboembolic disease.简短报告：一名患有严重血栓栓塞性疾病男孩的自身免疫性蛋白S缺乏症
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The role of abnormalities in the anticoagulant and fibrinolytic systems in retinal vascular occlusions.抗凝和纤溶系统异常在视网膜血管阻塞中的作用。
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Do medical conditions have an influence on central retinal vein occlusions?医学病症对视网膜中央静脉阻塞有影响吗？
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Retinal and choroidal vaso-occlusive disease in systemic lupus erythematosus associated with antiphospholipid antibodies.系统性红斑狼疮合并抗磷脂抗体时的视网膜和脉络膜血管闭塞性疾病
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Protein S and C4b-binding protein: components involved in the regulation of the protein C anticoagulant system.蛋白S和C4b结合蛋白：参与蛋白C抗凝系统调节的成分。
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