Puce A, Constable R T, Luby M L, McCarthy G, Nobre A C, Spencer D D, Gore J C, Allison T
Neuropsychology Laboratory, Veterans Affairs Medical Center, West Haven, Connecticut, USA.
J Neurosurg. 1995 Aug;83(2):262-70. doi: 10.3171/jns.1995.83.2.0262.
Functional magnetic resonance (MR) imaging was performed using a 1.5-tesla MR system to localize sensorimotor cortex. Six neurologically normal subjects were studied by means of axial gradient-echo images with a motor task and one or more sensory tasks: 1) electrical stimulation of the median nerve; 2) continuous brushing over the thenar region; and 3) pulsed flow of compressed air over the palm and digits. An increased MR signal was observed in or near the central sulcus, consistent with the location of primary sensory and motor cortex. Four patients were studied using echo planar imaging sequences and motor and sensory tasks. Three patients had focal refractory seizures secondary to a lesion impinging on sensorimotor cortex. Activation seen on functional MR imaging was coextensive with the location of the sensorimotor area determined by evoked potentials and electrical stimulation. Functional MR imaging provides a useful noninvasive method of localization and functional assessment of sensorimotor cortex.
使用1.5特斯拉磁共振（MR）系统进行功能磁共振成像，以定位感觉运动皮层。通过带有运动任务和一个或多个感觉任务的轴向梯度回波图像，对6名神经功能正常的受试者进行了研究：1）正中神经电刺激；2）在鱼际区域持续刷擦；3）在手掌和手指上脉冲式喷射压缩空气。在中央沟内或其附近观察到磁共振信号增强，这与初级感觉和运动皮层的位置一致。使用回波平面成像序列以及运动和感觉任务对4名患者进行了研究。3名患者患有继发于侵犯感觉运动皮层的病变的局灶性难治性癫痫。功能磁共振成像上看到的激活与通过诱发电位和电刺激确定的感觉运动区域位置一致。功能磁共振成像为感觉运动皮层的定位和功能评估提供了一种有用的非侵入性方法。
